Inductive sensing design challenge: Heamoglobin level sensing.

RE: Inductive sensing design challenge: Heamoglobin level sensing.

Former Member — Thu, 04 Dec 2014 04:04:42 GMT

wow interesting !!!

RE: Inductive sensing design challenge: Heamoglobin level sensing.

fahrenheit_98 — Wed, 14 May 2014 11:25:10 GMT

Hi Arun,

Your is a very interesting idea.

In the past I developed SPR biosensors so I have some experience in this field.

I have done some test with the LDC1000 and I have seen that it is very sensitive to contactless conductivity of liquid solutions (e.g. changing of salt concentration in the water). So I proposed to investigate about the possibility to use the LDC1000 as a biosensor.

In a biosensor it is very important the so called specificity: you need to distinguish the substance you are looking for (the analyte), from other substances.

In your case you should distinguish between the change in conductivity arising from different concentration of haemoglobin, from the conductivity of all the tissues immersed in the magnetic field. The presence of iron is irrelevant from a magnetic point of view.

Usually you need to create some specific enzymatic or immunological reaction with the analyte, measuring some phisical parameter (in this case the conductivity) and evaluating the values before and after the reaction. For the metals are often used chelating agents.

I hope this can help you.

Giuseppe

RE: Inductive sensing design challenge: Heamoglobin level sensing.

vsluiter — Mon, 12 May 2014 19:33:59 GMT

As stated earlier (can't find the link), I think the largest problem to be overcome is that -according to google- haemoglobin is NOT ferromagnetic. It would be nice to see whether you get ANY change when some blood is placed in the magnetic field.

RE: Inductive sensing design challenge: Heamoglobin level sensing.

waelect — Mon, 12 May 2014 11:55:28 GMT

I am not sure if this will help, but just in case the measurement could include other tissue, bone or other. Consider directing or blocking inductive sensing to cover only a small portion of the targeted area. It may not be an issue as I do not known much about the human anatomy. I have though work in Induction loop system and know that many components around the loop field are affected and can create weird results that are not wanted.

RE: Inductive sensing design challenge: Heamoglobin level sensing.

DAB — Sun, 11 May 2014 20:15:13 GMT

Interesting idea.

You might want to experiment with something like ferric chloride to see at what PPM you can detect the iron in solution.

You also might consider how salt and other body minerals in the blood will influence the results.

I had an idea similar to this but I just never had the time to do the work.

DAB