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Forum Stem cell based transplant, good or bad?
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  • stem_cells
  • medtronic
  • eavesdropper
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Stem cell based transplant, good or bad?

Eavesdropper
Eavesdropper over 14 years ago
imageimage
The operation in progress (left). Synthetic Windpipe section (right).
 
A man with tracheal cancer has recently had a windpipe transplant with one made from his own stem cells.
 
The surgery was performed on June 9th at the Karolinska University Hospital in Stockholm, Sweden. Professor Paolo Macchiarini said that this "is the first synthetic tissue engineered windpipe that has been successfully transplanted. Because the cells used to regenerate the trachea were the patient's own, there has been no rejection of the transplant and the patient is not taking (anti-rejection) drugs." The patient has been released today, 7/8/2011.
 
This is the first attempt at implanting a man made organ. First a nanocomposite tracheal scaffold was built by Alexander Seifalian from the University College London. Harvard Bioscience created a bioreactor that the scaffold was placed in for two days as the patients cells were grown across the framework. Macchiarini said that several surgeries of a similar nature are planned by the end of 2011.
 
The ease of growth and acceptance of implantation is proof that more research needs to be done on stem cells. A ban on stem cell research was lifted by President Obama back in June of 2009. Prior to then, former president Bush limited research due to his belief that he was defending human life (in reference to embryo stem cells).
 
With this achievement, are you for stem cell research? Or are you leaning towards the ban? And why either way?
 
Eavesdropper
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  • DAB
    0 DAB over 14 years ago

    It makes more sense to grow body parts from stem cells then it does to try to transplant them from donors.  Using your own or neutral cells is more acceptable to the body and the chances of rejection are much less.

    Reusing biological material is no different than reusing anyother resource available.  Stem cells exists to grow cells, not using them is a waste that condems many people to a very horrible death.  Plus finding acceptable donars is both difficult and prone to failure.  Stem cells provide a safe alternative without harming the donors or the person recieving the rebuilt organs.

    I watched my father die over eighteen months from stomach cancer.  Anyone who says that it is better to just throw stem cells away rather than save lives just does not understand the implications of their position.

     

    DAB

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  • Former Member
    0 Former Member over 14 years ago in reply to DAB

    I have seen some research where adult stem cells have been turned into other cell types, however they were then rejected by the body, similar to foreign body transplants.  There are still some kinks to be worked out, but I definitely look forward to some of the cures that can come from this research.  I am looking for someday my child not having to check blood sugar and give insulin just to survive.

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  • Eavesdropper
    0 Eavesdropper over 14 years ago in reply to Former Member

    Using a patients own stem cells to grow a part, as in the case above, has shown to be completely accepted by the body.

     

    I hope this case prompts major development in stem cell research. The world needs it, and the 10 year hiatus on in the USA was too long.

     

    E

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  • Former Member
    0 Former Member over 14 years ago in reply to Eavesdropper

    If you read an article published in Nature from a researcher at Oxford. http://www.nature.com/news/2011/110513/full/news.2011.286.html  It goes on to discuss a situation where the adult IPS were rejected by the same mouse they were grown from.  This isn't to say that they are completely rejected as in Embryonic versus Adult.  Just that it's something that is showing up.  Here is  a link to the specific letter from the research team.  http://www.nature.com/nature/journal/v474/n7350/full/nature10135.html   Yes I am also hoping that they can find the triggering source, that may lead to what might be happening with T1 diabetes and the attack on the Islet cells which causes it.

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  • Former Member
    0 Former Member over 14 years ago in reply to Eavesdropper

    If you read an article published in Nature from a researcher at Oxford. http://www.nature.com/news/2011/110513/full/news.2011.286.html  It goes on to discuss a situation where the adult IPS were rejected by the same mouse they were grown from.  This isn't to say that they are completely rejected as in Embryonic versus Adult.  Just that it's something that is showing up.  Here is  a link to the specific letter from the research team.  http://www.nature.com/nature/journal/v474/n7350/full/nature10135.html   Yes I am also hoping that they can find the triggering source, that may lead to what might be happening with T1 diabetes and the attack on the Islet cells which causes it.

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